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While your body generally cant store excess amounts of most water-soluble vitamins, vitamin B12 can remain in your body indefinitely, stored in your liver

To summarise, the black box of the biofiltration process in drinking water has not been illuminated yet

Ide et al reported that high-dose intrathecal methylcobalamin injection can relieve symptoms of paresthesia, burning pain, and heaviness in patients with diabetic neuropathy 23

doi:10.1016/j.otc.2020.03.011

If it is close to your next dose, skip the missed dose and continue your regular schedule

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