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Also, activation of PLA 2 can stimulate NAD(P)H oxidases (427) and increased PLA 2 activity has been reported to stimulate ROS generation in muscle mitochondria (281), cytosol (140) and release ROS into the extracellular space (433)

2025;43(16_suppl):5009.

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doi: 10.1155/2012/789174

Transcriptome analysis of long-term exposure to blue light in retinal pigment epithelial cells

These byproducts regulate enteroendocrine cell signaling, hormone release, and glucose and energy metabolism, reinforcing the microbiotas emerging role as a metabolically active endocrine organ [38]