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doi: 10.1111/apt.14384

Below are some of the top sites for B12 injections: Vastus Lateralis (Outer Thigh): Ideal for Self-Administration The vastus lateralis, located on the outer part of the thigh, is one of the most commonly recommended sites for self-administered Vitamin B12 injections

First, they suggest that AOD-9604 can be used for extended periods without loss of efficacy due to antibody neutralization

Vials are more cost-effective, but you reconstitute them yourself with bacteriostatic water

Absorption Injected free B12 diffuses through the extracellular fluid into nearby capillaries, enters the bloodstream and binds to TCII (transcobalamin II)

Cost remains high for brand-name formulations