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Within the region replaced in chimera M8, 34 amino acids are different between MRP1 and MRP2
, & Sikiric, P
In the original publication the models have been used for the analysis of drug targets, but these models allow analysis of the glutathione metabolism in parallel with the other changes in cancer metabolism
[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Moeslinger T., Brunner M., Volf I., Spieckermann P.G
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Thus, attempts at oral GSH treatments were known
