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These antibodies contribute to glandular injury via complement-dependent and antibody-dependent cell-mediated cytotoxicity, and promote the release of cytokines such as IL-6, IL-1, and IL-8, which enhance lymphocyte accumulation and the local inflammatory response

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Vitamin B12 may also play an important role in bone health, as studies have shown that low blood levels of B12 can be associated with an increased risk of osteoporosis in women

Sever et al., 2019), thus avoiding and directly counteracting VEGF tumorigenesis (Radeljak et al., 2004)

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