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Michael Trauner: Conceptualization, Writing- Original draft, Writing- Reviewing and Editing

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For the timepoint study ( n = 50), male and female APOE-TR mice were euthanized at three different timepoint (10-, 25-, and 50-weeks) for three homozygous genotypes: APOE2-TR, APOE3-TR, and APOE4-TR (Supplementary Table S1)