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Circulating oxidized and glycated LDLs (HOG-LDL) damage and induce apoptosis in vascular endothelial cells (EC), further promoting progression of atherosclerosis as well as other vascular complications of metabolic disorders (204, 205)

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In vitro findings showed antioxidant activity, strong collagenase inhibition, increased Type I collagen production, and enhanced expression of hyaluronan synthase proteins linked to skin hydration

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