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However, reports that relate antibody titres to disease progression involve relatively few patients 86,87,88 , and are confounded by the higher levels of antigen seen in severe infections that are predicted to drive a stronger immune response or a heightened innate inflammatory response

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4 Discussion Hypertension affects approximately 31.1% of adults worldwide and is a leading cause of premature death globally (42)

AGER-mediated lipid peroxidation drives caspase-11 inflammasome activation in sepsis

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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis