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acral or subungual areas

Imaging Examination CT of the brain revealed a 3.3 3.8 4cm heterogeneous mass with mildly increased density and a hyperdense rim

Multiple stimuli such as growth factors, cytokines, viruses, GPCR ligands and oncogenes can sequentially activate the ERK pathway and result in ERK1/2 phosphorylation that regulates different transcription factors, including c-FOS, cJUN, ELK-1, c-MYC, and ATF-2 controlling cell growth, migration, and differentiation [36]
