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Accordingly, the production rate (U/h) was calculated by dividing the HDT yield (U) by the time (h) in which the protein was sampled for the measurement

attempted to prevent hepatotoxicity in massive APAP overdoses by doubling the rate of NAC infusion over the last 16 hours, giving patients 12.5 mg/kg/h instead of the standard 6.25 mg/kg/h

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