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A common pathway affecting all these risk factors involves a low measure of reduced glutathione (i.e., GSH) level (Khanfar and Al Qaroot, 2020
The similarities in disease mechanisms across species are striking, and as a result, many veterinary drugs used to treat animals are either identical or closely related to those used for human treatment

Carmona-Ribeiro, Biocolloids Laboratory, Departamento de Bioqumica, Instituto de Qumica, Universidade de So Paulo, Av

3 Overview of ferroptosis Cell death is fundamental to organismal growth, development, senescence, and death, involving mechanisms such as apoptosis, necrotic apoptosis, autophagy, cellular pyroptosis, and necrosis, each with distinct characteristics (Moujalled et al., 2021)

Oxidative stress and neuroinflammation are hallmark features of stroke, significantly contributing to neuronal damage [104]

16 Selenium, identified as a toxic catalyst in 1817, was later found to be an essential component of the glutathione peroxidase (GPX) family, with GPX1 becoming widely accepted as a novel peroxidase in 1957
