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Pandit, P

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MD, mitochondrial dysfunction

The development of selective FGFR inhibitors for the treatment of locally advanced or metastatic cancers, such as pemigatinib (Pemazyre) for CCA, futibatinib (Lytgobi) for iCCA, and erdafitinib (Balversa) for urothelial carcinoma, has overcome some of the challenges presented by off-target toxicities associated with less selective FGFR inhibitors including dovitinib, lenvatinib (Lenvima), and ponatinib (Iclusig

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