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This trajectory mirrors the natural maturation of emotional resilience, with adolescence representing a period of peak anxiety vulnerability, followed by reduced susceptibility in adulthood [41,42,43,44]

In physiological conditions, HO is generated in vivo by peroxisomes, through the activity of various oxidative enzymes such as glucose oxidase and D-amino acid oxidase, or via the dismutation of superoxide radicals catalyzed by superoxide dismutase

These genes regulated by GSTM3 were mainly focused on metabolism, antioxidant activity and signal transduction

Changed SOD, MDA, CAT, and GST activities suggested OS (PS

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Antioxidant and Tissue Protection Copper is required for the function of several key antioxidant enzymes, including superoxide dismutase