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The addition of erastin or high extracellular glutamate levels reduced cysteine, which inhibited system Xc(-) and led to GPx-4 inactivation and ferroptosis induction (13)

Levodopa deactivates enzymes that regulate thiol-disulfide homeostasis and promotes neuronal cell death: implications for therapy of Parkinson's disease
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Understanding the serum Vitamin b12 level and its implications in treating neuropsychiatric conditions: an orthomolecular perspective

A less pronounced tissue expression of the protein was observed in tumour cells as compared to control (21)
