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Patients should be closely monitored during each injection and for at least one hour after the initial dose

It is noteworthy that PF-4708671 can inhibit p70S6K1 as shown by the diminished phosphorylation of its downstream target, ribosomal protein S6, even though the level of p70S6K1 phosphorylation increased (Fig

SRC Inhibition in Colorectal Cancer

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(October 2014)