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Description
Alternatively, Type I M-PDT, produces cytotoxic ROS such as superoxide anion radicals (O 2 - ) and hydroxyl radicals (OH) through electron transfer, with minimal oxygen dependence 39,40,41,42,43 , making it more suitable for hypoxic tumors
10.1161/CIRCRESAHA.118.313971 26
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Since both steps require the same substrate (CoA), they compete for it within the mitochondria [63]
