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Besides its function as a reducing agent and primary antioxidant 7 , GSH participates in several critical physiological processes, including cell proliferation, apoptosis, immune function, and fibrogenesis 8

130 Another study carried out on other cancer cells, including U373 MG, a GBM cell line, the hypoxia-induced UPR activated PERK (protein kinase RNA-like ER kinase) in the ER

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Ann Emerg Med 2000;36:12632

Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation