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These natural compounds offer potential protective strategies to maintain the redox homeostasis of melanocytes in conditions of potential pathologies, preventing the development of diseases, including cancer, but also therapeutic effects in pathological conditions

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Accordingly, while Nrf2-dependent activation of HO-1 is related to a protective and beneficial effect in neurons, this pathway drives the transcription of genes involved in iron quenching, chelation and transport (114, 115), as well as in prevention of lipid peroxidation (116, 117), resulting cytoprotective action on cells and tissues

[DOI] [PubMed] [Google Scholar] Berg GG, Miles EF

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In prokaryotic cells, the start codon codes for N-formyl-methionine carried by a special initiator tRNA