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10.1074/jbc.M101355200 J
Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population

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Studies on the mechanism of haloacetonitrile-induced gastrointestinal toxicity: Interaction of dibromoacetonitrile with glutathione and glutathione-s-transferase in rats

The subcutaneous tissue at that site becomes sensitised, and subsequent injections into the same area are progressively more uncomfortable
The precise molecular identity of these binding sites remains under active investigation, but their characterisation has strengthened the mechanistic basis for Semax's CNS activity and supported its classification as a compound with defined receptor-level pharmacology rather than merely non-specific neuromodulatory effects