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While further studies are needed to assess longterm safety, dosing, and clinical relevance, the work points to a promising intranasal drugdelivery platform that emphasizes stability, retention, and neuroprotectionkey considerations for managing a chronic neurodegenerative disease

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Elevation of NAD Levels One of the most important downstream effects of NNMT inhibition by 5-Amino-1MQ is the preservation and elevation of nicotinamide adenine dinucleotide (NAD)

Johnston KL, Clifford MN, Morgan LM
