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Description
PMID: 30268698
Nature 473 , 308316 (2011)
& Hewett, J
This differential susceptibility to peroxidation is the reason why MUFA and PUFA have antagonistic effects in ferroptosisenrichment with MUFA inhibits ferroptosis and enrichment with PUFA enhances ferroptosis [55]
However, it remains unclear if dysfunctional reactivity and contractility caused by G6PD def lead to a pathogenic phenotype in humans as G6PD def has been reported to be both cardio-protective and cardio-damaging [14,38]
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