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4 Transaminase Upregulation and Targeting Amino Acid Synthesis for Cancer Therapy Another means of inhibiting glutaminolysis is to target alanine transaminase through L-cycloserine or aspartate transaminase through the inhibitor amino oxyacetate, which could almost completely halt the growth of breast cancer in xenograft mice [117, 118]

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Moreover, riboflavin has been shown to directly stimulate the release of anti-inflammatory cytokines (e.g., IL-10, IL-12p70) and immune modulators (i.e., MCP-1, HMGB1, Hsp72, Hsp25) 49,50

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L., Van Ryzin R