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ZhuWGregoryJCOrgEBuffaJAGuptaNWangZet al

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Zhang Y, Wu M-J, Lu W-C, Li Y-C, Chang CJ, Yang J-Y
Conditions commonly associated with elevated LDL-P include: High triglycerides Low HDL-C Insulin resistance or type 2 diabetes Central obesity Non-alcoholic fatty liver disease (NAFLD) Additional contributors include: High intake of refined carbohydrates Sedentary lifestyle Weight gain (especially visceral fat) Hypothyroidism Chronic kidney disease Genetic predispositions (e.g., familial combined hyperlipidemia) Lipid profiles showing high triglycerides and low HDL-C should prompt consideration of elevated LDL-P, even if LDL-C appears normal

The highest concentrations of L- carnitine are typically found in skeletal and cardiac muscle tissue
Preclinical studies with human adipose tissue explants Advantages of using human adipose tissue explants White adipose tissue (WAT) in humans is heterogeneous, highly vascularized, and innervated connective tissue

Other approaches include ion mobility spectrometry (IMS) 36,37 and alternative gas-phase ion activation 38,39,40,41,42,43,44
