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Its antioxidant properties help neutralize free radicals caused by intense physical activity, which can reduce soreness and accelerate muscle recovery

Statements Author contributions ZJ: Writing original draft

Complex III can also generate O 2 and release it into the intermembrane space where the O 2 traverses through voltage-dependent anion channels (VDACs) into the cytosol and is converted into H 2 O 2 by SOD1

Alterations in the GM composition can lead to the disruption of the intestinal epithelial barrier, provoked by gut-derived compounds, which may permit microbes and microbiota-derived unhealthy metabolites to enter the circulation and be transported to the brain through the gut-brain axis [49, 50]

However, there are still major gaps in our understanding of how specific microbial compounds influence human conditions