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Modulates nitric oxide (NO) signaling It influences nitric oxide synthase activity, affecting vascular tone and tissue perfusion, which is essential for delivering oxygen and nutrients to healing tissues

Suppression of Drp1 with mitochondrial division inhibitor-1, rescued the decrement in mitochondrial length, thereby preventing hippocampal neuron apoptosis, and enhancing cognition in TBI (Fischer et al., 2016)

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Abbreviations: AIFM, apoptosis-inducing factor mitochondria associated 1

They assessed its efficacy by administering insulin via transdermal patches to diabetic rats