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In vitamin B12 deficiency, higher serum folate is associated with increased homocysteine and methylmalonic acid concentrations
On the other hand, the modulation of mitochondrial NAD + /NADH levels can impact lysosome functions during inflammatory T cell responses

J Biol Chem 280: 32485-32492

doi: 10.1023/A:1005537411244

Others, they only feel normal when they are hyperthyroid