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From protein, zinc can readily be made available but also made unavailable

Similarly, genetic deletion or pharmacological suppression of 5-lipoxygenase (5-LO) in mice led to induction of phase II detoxification enzyme SULT2A1 and inhibition of the pro-toxic phase I enzyme CYP 3A11, which subsequently reduced NAPQI formation and finally ameliorated AILI [94]

Epilepsy Behav 49:158163

doi: 10.1016/j.immuni.2013.02.003

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Local applications such as intratympanic and intracochlear injections, administering STS directly to the ear, are not the subject of this review