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In adipocytes and L6 cells, treatment with berberine showed AMPK activation, leading to the phosphorylation of ACC and inhibition of fatty acid synthesis

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Mol Cell Biol 19: 62866296, 1999

Ebert DH, Gabel HW, Robinson ND et al (2013) Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR