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showed that a specific mutation in p53 (3KR mutant that cannot be acetylated on certain lysine residues) causes cancer cells to lose the ability to induce cell cycle arrest or apoptosis

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Autophagic stress involves the dynamic interplay of cell formation, maturation, and degradation and helps to explain the seemingly contradictory roles that autophagy-related processes play in homeostasis, adaptation, degeneration, and even cell death

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