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This review highlights that given the robust preclinical evidence and high public interest, there is a critical need for well-designed human trials to assess the safety, efficacy, and clinical utility of BPC-157 in musculoskeletal medicine

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Human clinical evidence for TB-500 (a synthetic form of thymosin beta-4) is limited because most peer-reviewed studies involve the native peptide thymosin beta-4 in wound-healing settings rather than TB-500 specifically, but research does show its regenerative and anti-inflammatory effects in humans

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