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Injections are particularly appropriate for those with: Pernicious anaemia, an autoimmune condition affecting B12 absorption Conditions affecting the stomach or small intestine, such as Crohns disease or coeliac disease Those who have had gastric surgery or bariatric procedures Strict vegans and vegetarians not meeting their B12 needs through food or oral supplements For those who can absorb B12 normally, oral supplements are generally an effective and well-evidenced alternative to injections

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Nerve problems, such as numbness and tingling in the hands and feet, can also occur

If you're traveling internationally, research the destination country's pharmaceutical import laws before departure

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A typical protocol involves injections weekly for several weeks, then gradually reducing in frequency as levels stabilise