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Most notably, only the combined loss of the tumor suppressors RB1 and TP53 in genetic mouse models enables the lineage switching from AR-dependent luminal tumors to AR-independent neuroendocrine and basal-like cancers [44, 45]

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minor side effects include soreness at injection sites or mild nausea

Neurology 82(14):12311238

MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells

Neuron 109 , 31043118.e6 (2021)
