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10.1016/j.freeradbiomed.2014.10.741 7 BerntssenM

Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors

Maintaining a high GSH pool is essential for GPx activity, for direct radical scavenging, and for the function of GSH S-transferases in detoxification

Glutathione conjugation reactions could also be utilized to build the bioactive compounds observed in the process of synthesizing cysteinyl leukotrienes (CysLT) such as LTC4, LTD4, and LTE4

9 Insulin-like growth factor-binding protein complex acid labile subunit

Considering that, as described above, neurons have low MG detoxification capacity, the low protein expression levels of Pfkfb3 may be viewed as a neuronal regulatory mechanism preventing MG damages, since MG production is tightly dependent upon the glycolytic rate