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Hypoxia induces proliferation via NOX4-mediated oxidative stress and TGF-3 signaling in uterine leiomyoma cells

Lee RM, Antonoff M

Here we report that deletion of Aspergillus fumigatus egtA (AFUA_2G15650), which encodes a trimodular enzyme, abrogated EGT biosynthesis in this opportunistic pathogen

By specifically inhibiting the H+/K+-ATPase in the gastric parietal cell, the proton pump inhibitor esomeprazole reduces stomach acid output

Ongoing phase 3 trials are collecting long-term safety data to assess safety and efficacy