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The translocated cyt c hijacks histone chaperones such as suppressor of variegation, enhancer of zeste and trithorax (SET)/template-activating factor (TAF)-I, inhibiting the nucleosome assembly/disassembly activity and DNA repairing (Gonzlez-Arzola et al., 2015

Following statistical analysis to reduce the risk of false positive associations two genes remained that showed statistically significant differences between patients and controls on both SNP and gene expression analysis

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Euskirchen P, et al

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Knutsen, S