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Katherine Birchenough was one of the first physicians in South Carolina to be certified in functional medicine

35 Reduction in depressive symptoms and benefits in quality of life were also found in secondary analysis of other studies

Standard allometric scaling would suggest a far lower human-equivalent dose

Emerging therapeutic strategies for SLE extend beyond B cell depletion to target CD4 follicular helper T (Tfh) cells: E4BP4 inhibits Tfh differentiation by repressing BCL-6 transcription via recruitment of HDAC1 and EZH2, while impaired E4BP4 function and IFN-Idriven IL-21/IFN- production promote Tfh expansion and autoreactive B cell responses, supporting Tfh-directed CAR-T approaches (54, 55)

DYRK1B inhibition exerts senolytic effects on endothelial cells and rescues endothelial dysfunctions

10.1016/j.brainres.2008.01.079 293 YinZ.JiangH.LeeE