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During ferroptosis, when cancer cells are under ROS-induced stress and the antioxidant defense is dysfunctional in the tumor cellular environment, cancer cells shift energy from the OXPHOS pathway to the glycolysis pathway to support vital biological events such as macromolecular biosynthesis, membrane-protein integration and to maintain cross-membrane ion gradients and DNA replication [96]

To better assess quantification precision, we next calculated the mean squared error (MSE) as the sum of positive bias and variance for each method, which represent the quantification error in accuracy and precision, respectively (Fig

In 1971, it was reported that, in the presence of excess GSH, one molecule of CSSSC led to the reduction of at least 25 molecules of cytochrome c, implicating hydropersulfides as catalysts 30

Free electron generation via ionization mainly contributes to fs-laser plasma generation since thermal effects become negligible or non-existent in this regime ( t p eh )

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Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (82470841 to M.L.), Natural Science Foundation of Xiamen City, China (3502Z20227162 to M.L.) and Natural Science Foundation of Fujian Province, China (2023I0002 to M.L.)