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The combination of low B12 and elevated folate is particularly suggestive of small intestinal bacterial overgrowth

Early changes may include subtle improvements in body composition and slight reductions in waist circumference before significant weight loss occurs

Proper storage and handling are essential to ensure the peptide remains effective throughout the duration of the study

While early and smaller trials showed promising fat-loss effects, the largest Phase IIb trial did not achieve statistical significance in humans for its primary endpoint of weight reduction, which led to the program being discontinued

It remains experimental and is not FDA-approved as a therapy