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Efficacy of NNMT inhibitor 5-amino-1MQ in diet-induced obese (DIO) mice 17-week old, male DIO C57Bl/6 mice that have been fed high-fat diet (HFD) for 11 weeks (starting at week 6) were purchased from Jackson Labs (Jackson Laboratory

In addition to the methods described above, other technique can be applied to identify the Se compounds started with compound purification by ion-exchange chromatography, followed by identification of the molecular mass by Electrospray Ionization-Mass Spectrometry (ESI-MS) ( Bioactivity of Se compounds Generally, literature shows that organic Se species tend to have higher bioactivities, bio-accessibility and lower toxicity than inorganic Se species