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Subcutaneous or intramuscular: TB-500 is injected subcutaneously or intramuscularly depending on the indication
Hepatitis B core (HBc) VLPs are among the most insertion-tolerant carriers due to the inherent flexibility of their spike structures (Pumpens and Grens, 2001), allowing epitopes to be displayed at the N-terminus, C-terminus, or the major immunodominant region (MIR)

Naganawa, Lymphoplasmacytic sclerosing cholangitis: assessment of clinical, CT, and pathological findings, Clin

Hainsworth JD
Many advanced protocols combine multiple compounds from this list to capture synergistic benefits

So that might lead to some pain there, but it might also lead to some inability to move that joint or that limb as well as you could previously
