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Diabetes 68(8):1670-80 2019 PMC6692818 RISE Consortium

10.7759/cureus.19897

Alzheimer's disease is characterized by the formation of amyloid plaque in the brain and nerve cell degeneration
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Grade II HE is more readily discriminated using disorientation and asterixis as markers, which has led to a proposal by the International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) to term HE Grade II as Overt HE (OHE), whereas Grade 1 and mHE may be classed as Covert HE (CHE) [7]

In the brain, the interaction between dopamine and glutamate constitutes the pathological basis of psychiatric disorders [201]
