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Mc1r mice is acting through e/e MC4R , then Mc1r mice should have similar nociception to e/e ;MC4R / Mc1r and e/e MC4R null mice

Treusch S, Knuth S, Slaugenhaupt SA, Goldin E, Grant BD, Fares H: Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

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On average, 2030% of patients develop cirrhosis within 30 years (e3, e4)

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