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This shows a link between Al stress and MAPK activation (Mossor-Pietraszewska, 2001)

For peroxiredoxins, little data is available, but elevated levels of several isoforms were measured in plasma of individuals with T2D [267], and prevention of apoptosis of pancreatic-beta cells was reported [272]

It is particularly dependent on the activity of several enzymes but this activity can be inhibited rendering these enzymes inactive

doi: 10.1038/gt.2012.81 183 TraisterRSFabreSWangZXiaoXHirschR

Stucchi F, Li M, Castellano G, Cellesi F

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