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The distinction between CPT 20605 (intermediate joints) and CPT 20610 (major joints) matters most for elbow, wrist, and ankle claims: the primary large articulations at these locations (tibiotalar, humeroulnar, and radiocarpal) qualify for CPT 20610, while smaller associated articulations at the same anatomical region qualify for CPT 20605

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In these cases, peak benefits are usually felt after a series of regular injections over several weeks

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