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Pharmacological inhibitors of fatty acid synthase (FASN)-catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents

In cardiac surgery, randomized trials have reported inconsistent findings: one placebo-controlled study in 102 patients with chronic kidney disease, using postoperative serum creatinine change as the primary endpoint, found no renoprotective effect (267), whereas another trial in 70 patients undergoing coronary artery bypass grafting reported a reduction in AKI incidence with high-dose intravenous administration (268)

150 l wash buffer is added to increase the volume to over 400 l

Mitochondria contribute to both circuit properties and their variability by shaping the cellular processes on which circuit function depends

The glutathione-deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in -glutamylcysteine synthetase

[PubMed: 3286237] 57