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Moreover, p53 can increase the expression of spermine/spermine N1 acetyltransferase 1 (SAT1) and glutaminase 2 (GLS2), making cells more sensitive to ferroptosis, or promote ferroptosis by transcriptionally upregulating mitochondrial GLS2 [29]

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Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing wnt/beta-catenin signaling pathway

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The steps are reversible, with the equilibrium shifted toward product by the final deprotonation of the carboxylic acid

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HCT116 (ATCC, catalogue number CCL-247) cells were co-transfected with these two plasmids using polyethylenimine Max and screened for puromycin (0.5 g ml 1 ) resistance

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Studies have suggested that other clearance systems may exist, systems that do not require scavenging proteins

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Supporting this, Wu et al [35] described islet infiltration by CD8 + cytotoxic T cells and macrophages in type 2 diabetes, likely driven by chronic hyperglycaemia and hyperlipidaemia [36]

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