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Cell Sci 2013, 126, 16501658

Degradation is a gradual process, not a sudden event

The neuroprotective effect of EGCG against ischemia-induced brain damage was found, in part, due to the modulation of NOS isoforms and preservation of mitochondrial complex activity and integrity

Consistent with these mechanisms, it has been shown that breast cancer cells resistant to the growth inhibiting effects of rapamycin are also resistant to its chemosensitising effects (Mondesire et al, 2004), and sequence-dependent enhancement of paclitaxel cytotoxicity has also been seen with gefitinib and trastuzumab, agents that like mTOR inhibitors inhibit growth factor signal transduction (Lee et al, 2002

Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study

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