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The antioxidant enzymes of AsA-GSH pathway help in maintaining ROS homeostasis in cells by avoiding the potential cytotoxicity of ROS and allowing them to function as signal molecules
Cancer treatments significantly elevate OS through multiple mechanisms: chemotherapeutic agents, particularly alkylating agents and platinum compounds, generate excessive ROS directly damaging sperm DNA and membranes (87, 88), while radiation therapy induces both acute and chronic OS states in testicular tissue, leading to prolonged spermatogenic dysfunction (95)

Comparisons of treatment means when factors do not interact in two-factorial studies

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In 2006, researchers experimented on three groups of rats two controls and one intervention and observed that the group that received the Selank intervention exhibited significantly reduced anxiety-phobic states that persisted throughout the four-week study period
