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Omega-3 fatty acids modulate TRPV4 function through plasma membrane remodeling

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Aalhus J

While octadecapentaenoic acid (ODPA) can be observed in some alga (e.g., dinoflagellates), 72 it is generally not observed in mammals and ODPA-derived octadecanoids will not be discussed here

10.1186/s12263-022-00713-y Genes Nutr

CEBPB orchestrates immunosuppressive gene activation (Arg-1, COX2, NOS2, NOX2) by partnering with Lnc-17Rik to remodel the transcriptional repressor complex (LAP/LIP/CHOP), recruiting WDR5 for H3K4me3 enrichment at target promoters, thereby amplifying myeloid-derived suppressor cell function and tumor progression, with its human homolog exhibiting marked overexpression in myeloid-derived suppressor cells (MDSCs) from esophageal cancer patients [28]