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Macrophages with cellular backpacks for targeted drug delivery to the brain
Effect of ethanolic leaves extract of moringa oleifera on blood glucose levels of streptozocin-induced diabetics and normoglycemic wistar rats
An 8-week treadmill exercise at 70%85% VO 2 max significantly downregulated the levels of TFR1, TF, DMT1, FTL, FTH, mitochondrial Ferritin, -secretase, and APP in the cortical motor regions of aged amyloid precursor protein-C105 (APP-C105) mice, upregulated the expression of FPN1, Furin, and -secretase, significantly reduced Fe 2+ , Fe 3+ , and total iron content, inhibited brain iron accumulation and A plaque growth, thereby improving learning ability, memory, and cognitive function in aged APP-C105 mice (Choi et al., 2021)
The expanded CGG repeats can form stable secondary structures, such as hairpins, which disrupt normal transcriptional processes (217)
33 HigashitsujiY.AngererA.BerghausS.HoblB.MackM
